Stress, work environment and severity of chronic autoimmune/autoinflammatory disease (SWAD)

The scientific literature recognizes the significant impact of stress on the immune response, thus influencing the development and exacerbation of autoimmune/autoinflammatory diseases, particularly skin diseases. However, skin diseases, aggravated by occupational stress, remain little studied. The objective of this project is to A) describe the target population (portion of the CONSTANCES cohort affected by a diagnosis of autoinflammatory dermatosis); B) estimate exposure to the stress factors studied according to socio-professional category; C) evaluate the association between targeted stress factors and the severity of autoinflammatory dermatoses; D) examine this association simultaneously according to other factors of individual and environmental vulnerability.