The project aims to provide new epidemiological evidence on the association between DBPs and nitrate in drinking water with breast and colorectal cancer risk. Specifically, we will:
1) Ascertain drinking water source and treatment in the study areas for 1950-2019.
2) Model level of THMs, bromate, chlorate, chlorite and nitrate in drinking water.
3) Validate current routine monitoring data with own measurements.
4) Estimate long-term exposure to THM, bromate, chlorate, chlorite and nitrate in the study population.
5) Evaluate the breast and colorectal cancer risk associated with long-term exposure to THMs, bromate, chlorate, chlorite and nitrate, adjusting for confounders.